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there be this caution used, that when they be | reported entire, and dismembered by articles. Neithroughly sifted and brought to resolution, they be from thenceforth omitted, discarded, and not continued to cherish and encourage men in doubting. To which calendar of doubts or problems, I advise to be annexed another calendar, as much or more material, which is a calendar of popular errors, I mean chiefly in natural history, such as pass in speech and conceit, and are nevertheless apparently detected and convicted of untruth, that man's knowledge be not weakened nor embased by such dross and vanity.

Catalogus falsitatum grassantium in historia naturæ.

As for the doubts or non liquets general or in total, I understand those differences of opinions touching the principles of nature, and the fundamental points of the same, which have caused the diversity of sects, schools, and philosophies, as that of Empedocles, Pythagoras, Democritus, Parmenides, and the rest. For although Aristotle, as though he had been of the race of the Ottomans, thought he could not reign, except the first thing he did he killed all his brethren; yet to those that seek truth and not magistrality, it cannot but seem a matter of great profit, to see before them the several opinions touching the foundations of nature: not for any exact truth that can be expected in those theories: for as the same phænomena in astronomy are satisfied by the received astronomy of the diurnal motion, and the proper motions of the planets, with their eccentrics, and epicycles; and likewise by the theory of Copernicus, who supposed the earth to move, and the calculations are indifferently agreeable to both so the ordinary face and view of experience is many times satisfied by several theories and philosophies; whereas to find the real truth requireth another manner of severity and attention. For, as Aristotle saith, that children at the first will call every woman mother, but afterward they come to distinguish according to truth: so experience, if it be in childhood, will call every philosophy mother, but when it cometh to ripeness, it will discern the true mother; so as in the mean time it is good to see the several glosses and opinions upon nature, whereof it may be every one in some one point hath seen clearer than his fellows; therefore I wish some collection to be made painfully and understandingly de antiquis philosophiis, out of all the De antiquis philosophiis. possible light which remaineth to us of

them: which kind of work I find deficient. But here I must give warning, that it be done distinctly and severally, the philosophies of every one throughout by themselves, and not by titles packed and fagotted up together, as hath been done by Plutarch. For it is the harmony of a philosophy in itself, which giveth it light and credence; whereas if it be singled and broken, it will seem more foreign and dissonant. For as when I read in Tacitus the actions of Nero or Claudius, with circumstances of times, inducements, and occasions, I find them not so strange; but when I read them in Suetonius Tranquillus, gathered into titles and bundles, and not in order of time, they seem more monstrous and incredible; so is it of any philosophy

ther do I exclude opinions of latter times to be likewise represented in this calendar of sects of philosophy, as that of Theophrastus Paracelsus, eloquently reduced into a harmony by the pen of Severinus the Dane, and that of Tilesius, and his scholar Donius, being as a pastoral philosophy, full of sense, but of no great depth: and that of Fracastorius, who though he pretended not to make any new philosophy, yet did use the absoluteness of his own sense upon the old and that of Gilbertus, our countryman, who revived, with some alterations and demonstrations, the opinions of Xenophanes: and any other worthy to be admitted.

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Thus have we now dealt with two of the three beams of man's knowledge, that is, Radius directus, which is referred to nature; Radius refractus, which is referred to God, and cannot report truly because of the inequality of the medium; there resteth Radius reflexus, whereby man beholdeth and contemplateth himself.

WE come therefore now to that knowledge whereunto the ancient oracle directeth us, which is the knowledge of ourselves; which deserveth the more accurate handling, by how much it toucheth us more nearly. This knowledge, as it is the end and term of natural philosophy in the intention of man, so, notwithstanding, it is but a portion of natural philosophy in the continent of nature; and generally let this be a rule, that all partitions of knowledges be accepted rather for lines and veins, than for sections and separations; and that the continuance and entireness of knowledge be preserved. For the contrary hereof hath made particular sciences to become barren, shallow, and erroneous, while they have not been nourished and maintained from the common fountain. So we see Cicero the orator complained of Socrates and his school, that he was the first that separated philosophy and rhetoric, whereupon rhetoric became an empty and verbal art. So we may see, that the opinion of Copernicus touching the rotation of the earth, which astronomy itself cannot correct, because it is not repugnant to any of the phænomena, yet natural philosophy may correct. So we see also that the science of medicine, if it be destitute and forsaken by natural philosophy, it is not much better than an empirical practice.

With this reservation therefore we proceed to Human Philosophy, or humanity, which hath two parts: the one considereth man segregate or distributively; the other congregate or in society. So as human philosophy is either simple and particular, or conjugate and civil. Humanity particular consisteth of the same parts whereof man consisteth, that is, of knowledges which respect the body, and of knowledges that respect the mind; but before we distribute so far, it is good to constitute. For I do take the consideration in general, and at large, of human nature to be fit to be emancipated and made a knowledge by itself; not so much in regard of those delightful and elegant discourses which have been made of the dignity of man, of his miseries, of his state and life, and the like adjuncts of his

common and undivided nature; but chiefly in regard | clean for meat, are many and strict. Nay the faith of the knowledge concerning the sympathies and concordances between the mind and body, which being mixed, cannot be properly assigned to the sciences of either.

This knowledge hath two branches: for as all leagues and amities consist of mutual intelligence and mutual offices, so this league of mind and body hath these two parts, how the one discloseth the other, and how the one worketh upon the other; | Discovery, and Impression.

The former of these hath begotten two arts, both of prediction or prenotion, whereof the one is honoured with the inquiry of Aristotle, and the other of Hippocrates. And although they have of later time been used to be coupled with superstitious and fantastical arts, yet being purged and restored to their true state, they have both of them a solid ground in nature, and a profitable use in life. The first is physiognomy, which discovereth Pars physiognomiæ, de ges the disposition of the mind by the linea tu sive motu ments of the body. The second is the corporis. exposition of natural dreams, which discovereth the state of the body by the imaginations of the mind. In the former of these I note a deficience, for Aristotle hath very ingeniously and diligently handled the factures of the body, but not the gestures of the body, which are no less comprehensible by art, and of greater use and advantage. For the linea ments of the body do disclose the disposition and inclination of the mind in general; but the motions of the countenance and parts do not only so, but do farther disclose the present humour and state of the mind and will. For, as your majesty saith most aptly and elegantly, "As the tongue speaketh to the ear, so the gesture speaketh to the eye." And therefore a number of subtle persons, whose eyes do dwell upon the faces and fashions of men, do well know the advantage of this observation, as being most part of their ability; neither can it be denied but that it is a great discovery of dissimulations, and a great direction in business.

The latter branch, touching impression, hath not been collected into art, but hath been handled dispersedly; and it hath the same relation or antistrophe that the former hath. For the consideration is double; "Either how, and how far the humours and effects of the body do alter or work upon the mind; or again, How, and how far the passions or apprehensions of the mind do alter or work upon the body." The former of these hath been inquired and considered, as a part and appendix of medicine, but much more as a part of religion or superstition: for the physician prescribeth cures of the mind in frenzies and melancholy passions, and pretendeth also to exhibit medicines to exhilarate the mind, to confirm the courage, to clarify the wits, to corroborate the memory, and the like: but the scruples and superstitions of diet, and other regiment of the body, in the sect of the Pythagoreans, in the heresy of the Manicheans, and in the law of Mahomet, do exceed so likewise the ordinances in the ceremonial law, interdicting the eating of the blood and the fat, distinguishing between beasts clean and un

itself, being clear and serene from all clouds of ceremony, yet retaineth the use of fastings, abstinences, and other macerations and humiliations of the body, as things real and not figurative. The root and life of all which prescripts is, besides the ceremony, the consideration of that dependency which the affections of the mind are submitted unto upon the state and disposition of the body. And if any man of weak judgment do conceive, that this suffering of the mind from the body, doth either question the immortality, or derogate from the sovereignty of the soul, he may be taught in easy instances, that the infant in the mother's womb is compatible with the mother, and yet separable; and the most absolute monarch is sometimes led by his servants, and yet without subjection. As for the reciprocal knowledge, which is the operation of the conceits and passions of the mind upon the body; we see all wise physicians, in the prescriptions of their regiments. to their patients, do ever consider accidentia animi, as of great force to further or hinder remedies, or recoveries; and more especially it is an inquiry of great depth and worth concerning imagination, how, and how far it altereth the body proper of the imaginant. For although it hath a manifest power to hurt, it followeth not it hath the same degree of power to help; no more than a man can conclude, that because there be pestilent airs, able suddenly to kill a man in health, therefore there should be sovereign airs, able suddenly to cure a man in sickness. But the inquisition of this part is of great use, though it needeth, as Socrates said, a Delian diver," being difficult and profound. But unto all this knowledge de communi vinculo, of the concordances between the mind and the body, that part of inquiry is most necessary, which considereth of the seats and domiciles which the several faculties of the mind do take and occupate in the organs of the body; which knowledge hath been attempted, and is controverted, and deserveth to be much better inquired. For the opinion of Plato, who placed the understanding in the brain, animosity (which he did unfitly call anger, having a greater mixture with pride) in the heart, and concupiscence or sensuality in the liver, deserveth not to be despised, but much less to be allowed. So then we have constituted, as in our own wish and advice, the inquiry touching human nature entire, as a just portion of knowledge to be handled apart.

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The knowledge that concerneth man's Body, is divided as the good of man's body is divided, unto which it referreth. The good of man's body is of four kinds, health, beauty, strength, and pleasure: so the knowledges are medicine, or art of cure; art of decoration, which is called cosmetic; art of activity, which is called athletic; and art voluptuary, which Tacitus truly calleth "eruditus luxus." This subject of man's body is of all other things in nature most susceptible of remedy; but then that remedy is most susceptible of error. For the same subtilty of the subject doth cause large possibility, and easy failing; and therefore the inquiry ought to be the

more exact.

To speak therefore of medicine, and to resume that we have said, ascending a little higher; the ancient opinion that man was microcosmus, an abstract or model of the world, hath been fantastically strained by Paracelsus and the alchemists, as if there were to be found in man's body certain correspondences and parallels, which should have respect to all varieties of things, as stars, planets, minerals, which are extant in the great world. But thus much is evidently true, that of all substances which nature hath produced, man's body is the most extremely compounded. For we see herbs and plants are nourished by earth and water; beasts for the most part by herbs and fruits; man by the flesh of beasts, birds, fishes, herbs, grains, fruits, water, and the manifold alterations, dressings, and preparations of these several bodies, before they come to be his food and aliment. Add hereunto, that beasts have a more simple order of life, and less change of affections to work upon their bodies; whereas man, in his mansion, sleep, exercise, passions, hath infinite variations; and it cannot be denied, but that the body of man of all other things is of the most compounded mass. The soul on the other side is the simplest of substances, as is well expressed;

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Purumque reliquit

Ethereum sensum, atque auraï simplicis ignem." So that it is no marvel though the soul so placed enjoy no rest, if that principle be true, that "Motus rerum est rapidus extra locum, placidus in loco." But to the purpose: this variable composition of man's body hath made it an instrument easy to distemper, and therefore the poets did well to conjoin music and medicine in Apollo, because the office of medicine is but to tune this curious harp of man's body, and to reduce it to harmony. So then the subject being so variable, hath made the art by consequence more conjectural; and the art being conjectural, hath made so much the more place to be left for imposture. For almost all other arts and sciences are judged by acts or master-pieces, as I may term them, and not by the successes and events. The lawyer is judged by the virtue of his pleading, and not by the issue of the cause. The master of the ship is judged by the directing his course aright, and not by the fortune of the voyage. But the physician, and perhaps the politician, hath no particular acts demonstrative of his ability, but is judged most by the event; which is ever but as it is taken: for who can tell, if a patient die or recover, or if a state be preserved or ruined, whether it be art or accident? And therefore many times the impostor is prized, and the man of virtue taxed. Nay, we see the weakness and credulity of men is such, as they will often prefer a mountebank or witch before a learned physician. And therefore the poets were clear-sighted in discerning this extreme folly, when they made Esculapius and Circe brother and sister, both children of the sun, as in the verses, En. vii. 772.

"Ipse repertorem medicinæ talis et artis Fulmine Phœbigenam Stygias detrusit ad undas:" And again, Æn. vii. 11.

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"Dives inaccessos ubi solis filia lucos," etc. For in all times, in the opinion of the multitude, witches, and old women, and impostors, have had a competition with physicians. And what followeth ? Even this; that physicians say to themselves, as Solomon expresseth it upon a higher occasion "If it befall to me, as befalleth to the fools, why should I labour to be more wise?" And therefore I cannot much blame physicians, that they use commonly to intend some other art or practice, which they fancy more than their profession. For you shall have of them, antiquaries, poets, humanists, statesmen, merchants, divines, and in every of these better seen than in their profession; and no doubt, upon this ground, that they find that mediocrity and excellency in their art maketh no difference in profit or reputation towards their fortune; for the weakness of patients, and sweetness of life, and nature of hope, maketh men depend on physicians with all their defects. But, nevertheless, these things, which we have spoken of, are courses begotten between a little occasion, and a great deal of sloth and default; for if we will excite and awake our observation, we shall see, in familiar instances, what a predominant faculty the subtilty of spirit hath over the variety of matter or form: nothing more variable than faces and countenances, yet men can bear in memory the infinite distinctions of them; nay, a painter with a few shells of colours, and the benefit of his eye, and habit of his imagination, can imitate them all that ever have been, are, or may be, if they were brought before him. Nothing more variable than voices, yet men can likewise discern them personally; nay, you shall have a buffoon, or pantomimus, will express as many as he pleaseth. Nothing more variable than the differing sounds of words, yet men have found the way to reduce them to a few simple letters. So that it is not the insufficiency or incapacity of man's mind, but it is the remote standing or placing thereof, that breedeth these mazes and incomprehensions: for as the sense afar off is full of mistaking, but is exact at hand, so is it of the understanding; the remedy whereof is not to quicken or strengthen the organ, but to go nearer to the object; and therefore there is no doubt, but if the physicians will learn and use the true approaches and avenues of nature, they may assume as much as the poet saith:

"Et quoniam variant morbi, variabimus artes:
Mille mali species, mille salutis erunt."

Which that they should do, the nobleness of their art doth deserve, well shadowed by the poets, in that they made Esculapius to be the son of the Sun, the one being the fountain of life, the other as the second stream; but infinitely more honoured by the example of our Saviour, who made the body of man the object of his miracles, as the soul was the object of his doctrine. For we read not that ever he vouchsafed to do any miracle about honour or money, except that one for giving tribute to Cæsar, but only about the preserving, sustaining, and healing the body of man.

Medicine is a science which hath been, as we

have said, more professed than laboured, and yet more laboured than advanced; the labour having been, in my judgment, rather in circle than in progression. For I find much iteration, but small addition. It considereth the causes of diseases, with the occasions or impulsions; the diseases themselves, with the accidents; and the cures, with the preservations. The deficiencies which I think good to note, being a few of many, and those such as are of a more open and manifest nature, I will enumerate and not place.

Narrationes medicinales.

The first is the discontinuance of the ancient and serious diligence of Hippocrates, which used to set down a narrative of the special cases of his patients, and how they proceeded, and how they were judged by recovery or death. Therefore having an example proper in the father of the art, I shall not need to allege an example foreign, of the wisdom of the lawyers who are careful to report new cases and decisions for the direction of future judgments. This continuance of Medicinal History I find deficient, which I understand neither to be so infinite as to extend to every common case, nor so reserved, as to admit none but wonders; for many things are new in the manner, which are not new in the kind; and if men will intend to observe, they shall find much worthy to observe.

Anatemia comparata.

In the inquiry which is made by anatomy, I find much deficience: for they inquire of the parts, and their substances, figures, and collocations; but they inquire not of the diversities of the parts, the secrecies of the passages, and the seats or nestlings of the humours, nor much of the footsteps and impressions of diseases; the reason of which omission I suppose to be, because the first inquiry may be satisfied in the view of one or a few anatomies; but the latter, being comparative and casual, must arise from the view of many. And as to the diversity of parts, there is no doubt but the facture or framing of the inward parts is as full of difference as the outward, and in that is the cause continent of many diseases, which not being observed, they quarrel many times with the humours, which are not in fault, the fault being in the very frame and mechanic of the part, which cannot be removed by medicine alterative, but must be accommodated and palliated by diets and medicines familiar. And for the passages and pores, it is true, which was anciently noted, that the more subtile of them appear not in anatomies, because they are shut and latent in dead bodies, though they be open and manifest in life: which being supposed, though the inhumanity of anatomia vivorum was by Celsus justly reproved; yet in regard of the great use of this observation, the inquiry needed not by him so slightly to have been relinquished altogether, or referred to the casual practices of surgery, but might have been well diverted upon dissection of beasts alive, which, notwithstanding the dissimilitude of their parts, may sufficiently satisfy this inquiry. And for the humours, they are commonly passed over in anatomies as purgaments, whereas it is most necessary to observe, what cavities, nests,

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and receptacles the humours do find in the parts, with the differing kind of the humour so lodged and received. And as for the footsteps of diseases, and their devastations of the inward parts, imposthumations, exulcerations, discontinuations, putrefactions, consumptions, contractions, extensions, convulsions, dislocations, obstructions, repletions, together with all preternatural substances, as stones, carnosities, excrescences, worms, and the like; they ought to have been exactly observed by multitude of anatomies, and the contribution of men's several experiences, and carefully set down, both historically, according to the appearances, and artificially, with a reference to the diseases and symptoms which resulted from them, in case where the anatomy is of a defunct patient: whereas now, upon opening of bodies, they are passed over slightly and in silence. In the inquiry of diseases they do Inquisitio abandon the cures of many, some as in ulterior de their nature incurable, and others as morbis insapast the period of cure; so that Sylla and the triumvirs never proscribed so many men to die, as they do by their ignorant edicts, whereof numbers do escape with less difficulty, than they did in the Roman proscriptions. Therefore I will not doubt to note as a deficience, that they inquire not the perfect cures of many diseases, or extremities of diseases, but pronouncing them incurable, do enact a law of neglect, and exempt ignorance from discredit.

nabilibus.

exteriore.

Nay farther, I esteem it the office of De euthanasia a physician not only to restore health, but to mitigate pain and dolors, and not only when such mitigation may conduce to recovery, but when it may serve to make a fair and easy passage: for it is no small felicity which Augustus Cæsar was wont to wish to himself, that same euthanasia; and which was specially noted in the death of Antoninus Pius, whose death was after the fashion and semblance of a kindly and pleasant sleep. So it is written of Epicurus, that after his disease was judged desperate, he drowned his stomach and senses with a large draught and ingurgitation of wine; whereupon the epigram was made, "Hinc Stygias ebrius hausit aquas:" he was not sober enough to taste any bitterness of the Stygian water. But the physicians, contrariwise, do make a kind of a scruple and religion to stay with the patient after the disease is deplored; whereas, in my judgment, they ought both to inquire the skill, and to give the attendances for the facilitating and assuaging of the pains and agonies of death.

les.

In the consideration of the cures of Medicinæ diseases, I find a deficience in the experimentareceipts of propriety, respecting the particular cures of diseases; for the physicians have frustrated the fruit of tradition and experience by their magistralities, in adding, and taking out, and changing quid pro quo, in their receipts, at their pleasures, commanding so over the medicine, as the medicine cannot command over the disease; for except it be treacle, and mithridatum, and of late diascordium, and a few more, they tie themselves to no receipts severely and religiously for

as to the confections of sale which are in the shops, For Cosmetic, it hath parts civil, and parts effemithey are for readiness, and not for propriety; for nate: for cleanness of body was ever esteemed to they are upon general intentions of purging, open-proceed from a due reverence to God, to society, and ing, comforting, altering, and not much appropriated to ourselves. As for artificial decoration, it is well to particular diseases; and this is the cause why worthy of the deficiencies which it hath; being neiempirics and old women are more happy many ther fine enough to deceive, nor handsome to use, times in their cures than learned physicians, because nor wholesome to please. they are more religious in holding their medicines. Therefore here is the deficience which I find, that physicians have not, partly out of their own practice, partly out of the constant probations reported in books, and partly out of the traditions of empirics, set down and delivered over certain experimental medicines for the cure of particular diseases, besides their own conjectural and magistral descriptions. For as they were the men of the best composition in the state of Rome, which either being consuls inclined to the people, or being tribunes inclined to the senate; so in the matter we now handle, they be the best physicians, which being learned, incline to the traditions of experience, or being empirics, incline to the methods of learning.

Imitatio na

turæ in balneis, et aquis medicinalibus.

In preparation of medicines, I do find strange, especially, considering how mineral medicines have been extolled, and that they are safer for the outward than inward parts, that no man hath sought to make an imitation by art of natural baths, and medicinable fountains: which nevertheless are confessed to receive their virtues from minerals; and not so only, but discerned and distinguished from what particular mineral they receive tincture, as sulphur, vitriol, steel, or the like; which nature, if it may be reduced to compositions of art, both the variety of them will be increased, and the temper of them will be more commanded.

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de vicibus medicinarum.

this part with the note of one deficience more, which seemeth to me of greatest consequence; which is, that the prescripts in use are too compendious to attain their end; for to my understanding, it is a vain and flattering opinion to think any medicine can be so sovereign, or so happy, as that the receipt or use of it can work any great effect upon the body of man: it were a strange speech, which spoken, or spoken oft, should reclaim a man from a vice to which he were by nature subject; it is order, pursuit, sequence, and interchange of application, which is mighty in nature; which although | it require more exact knowledge in prescribing, and more precise obedience in observing, yet is recompensed with the magnitude of effects. And although a man would think by the daily visitations of the physicians, that there were a pursuance in the cure; yet let a man look into their prescripts and ministrations, and he shall find them but inconstancies, and every day's devices, without any settled providence or project; not that every scrupulous or superstitious prescript is effectual, no more than every strait way is the way to heaven, but the truth of the direction must precede severity of observance.

For Athletic, I take the subject of it largely, that is to say, for any point of ability, whereunto the body of man may be brought, whether it be of activity, or of patience; whereof activity hath two parts, strength and swiftness and patience likewise hath two parts, hardness against wants and extremities, and endurance of pain and torment, whereof we see the practices in tumblers, in savages, and in those that suffer punishment: nay, if there be any other faculty which falls not within any of the former divisions, as in those that dive, that obtain a strange power of containing respiration, and the like, I refer it to this part. Of these things the practices are known, but the philosophy that concerneth them is not much inquired; the rather, I think, because they are supposed to be obtained, either by an aptness of nature, which cannot be taught, or only by continual custom, which is soon prescribed; which though it be not true, yet I forbear to note any deficiences, for the Olympian games are down long since, and the mediocrity of these things is for use; as for the excellency of them, it serveth for the most part but for mercenary ostentation.

For arts of Pleasure sensual, the chief deficience in them is of laws to repress them. For as it hath been well observed, that the arts which flourish in times while virtue is in growth, are military, and while virtue is in state, are liberal, and while virtue is in declination, are voluptuary; so I doubt, that this age of the world is somewhat upon the descent of the wheel. With arts voluptuary I couple practices jocular; for the deceiving of the senses is one of the pleasures of the senses. As for games

of recreation, I hold them to belong to civil life and education. And thus much of that particular human philosophy which concerns the body, which is but the tabernacle of the mind.

FOR Human Knowledge, which concerns the Mind, it hath two parts, the one that inquireth of the substance or nature of the soul or mind; the other that inquireth of the faculties or functions thereof.

Unto the first of these, the considerations of the original of the soul, whether it be native or adventive, and how far it is exempted from laws of matter, and of the immortality thereof, and many other points, do appertain; which have been not more laboriously inquired than variously reported; so as the travail therein taken seemeth to have been rather in a maze than in a way. But although I am of opinion, that this knowledge may be more really and soundly inquired even in nature than it hath been; yet I hold, that in the end it must be bounded by religion, or else it will be subject to deceit and delusion: for as the substance of the soul in the creation was not extracted out of the mass of heaven

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