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Characteristics of SelfAdministration
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abstinence syndrome acetylcholine action agonist-antagonists agonists amphetamine analgesia analgesic analgesic activity anesthetic animals anxiety barbiturates Beecher behavior benzomorphan binding brain cannabinoids cannabis changes Chem chronic Clin clinical cocaine codeine compounds cyclazocine decrease depolarization depression dose of morphine drinking drug dependence drug intake effects of alcohol effects of opiates ethanol euphoria excitatory experimental factors former addicts function GABA heroin hydroxyl increased inhibition inhibitory injection dose interaction intoxication intravenous Jasinski marihuana Martin Meisch Mello membrane Mendelson meperidine metabolism methadone mg/kg molecule morphinans morphine nalorphine naloxone narcotic antagonist neurons Nicoll nociceptive nociceptive stimulus observed opiate opiate administration opiate agonists pain patients pentazocine pentobarbital pethidines Pharmacol pharmacological physical dependence physiological Pickens placebo postsynaptic potency potential presynaptic produce Psychopharmacologia rats reaction reflex reinforcement release reported respiratory response rhesus monkeys self-administration sleep spinal structure studies substitution synaptic tetrahydrocannabinol Ther Thompson tion tolerance transmitter vivo Wikler withdrawal