NatureSir Norman Lockyer Macmillan Journals Limited, 2007 - Science |
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Page 321
... SUMOylation . Here we report that in rat hippocampal neurons multiple SUMOylation targets are pre- sent at synapses and we show that the kainate receptor subunit GluR6 is a SUMO substrate . SUMOylation of GluR6 regulates endocytosis of ...
... SUMOylation . Here we report that in rat hippocampal neurons multiple SUMOylation targets are pre- sent at synapses and we show that the kainate receptor subunit GluR6 is a SUMO substrate . SUMOylation of GluR6 regulates endocytosis of ...
Page 322
... SUMOylation assay12 to determine whether K886 within the consensus SUMOylation motif on GluR6a is the site of SUMOylation . Wild - type , but not K886R , C - terminal GluR6a was robustly SUMOylated ( Fig . 3c ) . To evaluate the role of ...
... SUMOylation assay12 to determine whether K886 within the consensus SUMOylation motif on GluR6a is the site of SUMOylation . Wild - type , but not K886R , C - terminal GluR6a was robustly SUMOylated ( Fig . 3c ) . To evaluate the role of ...
Page 323
... SUMOylation in a time - dependent manner . In contrast , 30 μM NMDA does not change the SUMOylation state of GluR6 . Lower panels show an immunoblot of total ẞ - actin as a control of protein loading . b , Quantification of kainate and ...
... SUMOylation in a time - dependent manner . In contrast , 30 μM NMDA does not change the SUMOylation state of GluR6 . Lower panels show an immunoblot of total ẞ - actin as a control of protein loading . b , Quantification of kainate and ...
Contents
ARTICLES | 53 |
LETTERS | 64 |
Chemical characterization of element 112 | 72 |
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activity analysis applications Arabidopsis assays biochar Biol biology biomedical brain CagA cancer candidate cell biology centre chemical chitin chromosome cilia clinical complex density detection diatreme diseases dystrophin e-mail electron Enceladus endosperm energy eutherian evolution experience expression function funding gene genetic global GluR6 hair follicles hClp1 human genome immune Immunology infection Institute interaction kimberlite kinase Laboratory levels macrophages magma magnetic Medical Medicine mice microarray microRNAs molecular molecules mRNA mutant Nature Nature Publishing Group naturejobs Nbs1AC/AC neurons observed Ocean olivine opossum paper at www.nature.com/nature pathogens phosphorylation Phys plants polarity position protein region role samples says Science scientific scientists sequence signal siRNA species spin spintronics stem cells structure studies substrate SUMOylation Supplementary Fig Supplementary Information surface synteny target temperature tion University variation wild-type yeast