Fundamental ImmunologyWilliam E. Paul The textbook that has defined the field of immunology since 1984 is now in its thoroughly revised and updated Sixth Edition. This comprehensive, up-to-date text will be of interest to graduate students,post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians, and any physician treating diseases in which immunologic mechanisms play a role. This edition features expanded coverage of regulatory T cells, innate immunity, and dendritic cells. Additional chapters on cytokines are also included. A companion Website offers the fully searchable text, plus all illustrations in full color and comprehensive lists of references. (www.fundamentalimmunology.com) |
Contents
T LYMPHOCYTES | 313 |
INTRODUCTION 1 | 363 |
The Immune System 1 Gary A Koretzky | 372 |
ORGANIZATION AND EVOLUTION | 407 |
THE INTERSECTION OF INNATE | 427 |
Dendritic Cells | 451 |
Antigenantibody Interactions and 17 NKT Cells and Other Innatelike T and | 518 |
Molecular Genetics 192 Siamon Gordon | 547 |
Type I Cytokines and Interferons and Their 37 Immune Responses to Intracellular | 1165 |
Interleukin1 Family of Ligands and 38 Immunity to Extracellular Bacteria | 1182 |
TNFRelated Cytokines in Immunity 776 Norman L Letvin | 1233 |
IMMUNOLOGIC MECHANISMS | 1291 |
Ronald H Schwartz | 1331 |
RegulatorySuppressor T Cells 943 Matthias G von Herrath and Dirk Homann | 1379 |
The Mucosal Immune System 983 Disease 1375 | 1426 |
Neural Immune Interactions 1031 Megan Sykes Kathryn Wood and David H Sachs | 1489 |
Structure Function | 570 |
FUNCTIONS OF THE IMMUNE RESPONSE 631 AGENTS | 1097 |
Fc Receptors and Their Role in Immune Thomas A Wynn | 1131 |
Reinhard Würzner Heribert Stoiber | 1523 |
| 1553 | |
Common terms and phrases
adaptive immune affinity antigen antigen receptor antigen-specific autoimmune BCR signaling binding bone marrow CD4+ T cells CD8+ CDR3 cell activation cell development cell receptor cell responses cell surface chemokines complex cytokines dendritic cells differentiation diversity domains effector encoded Figure function germline heavy chain helper T cells human immune response immune system immunoglobulin induced infection innate immune interaction isotype kinase ligand light chain lineage lipid rafts locus lymph nodes lymphocytes lymphoid organs lymphoid tissues macrophages mature mediated membrane memory B cell mice molecular mouse murine mutation naïve Nat Immunol Natl Acad Sci NK cells pathogens pathway peptide phosphorylation positive selection precursors Proc Natl Acad protein rearrangement recognition recombination region regulation repertoire Rev Immunol role sequences somatic specific spleen structure subsets switch T-cell target thymic thymocytes thymus tion transcription factor transgenic tyrosine V(D)J recombination vertebrates vitro vivo