Nature, Volume 452Sir Norman Lockyer Macmillan Journals Limited, 2008 - Electronic journals |
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Page 323
... mouse embryonic fibroblasts ( MEFs ) and mice deficient in 4E - BP1 and 4E - BP2 . Virus infection is suppressed in 4E - BP1 ̄ / ̄ 4E - BP2 ̄ / ̄ MEFs To study the role of 4E - BPs in the cell's response to virus infections ex vivo , MEFs ...
... mouse embryonic fibroblasts ( MEFs ) and mice deficient in 4E - BP1 and 4E - BP2 . Virus infection is suppressed in 4E - BP1 ̄ / ̄ 4E - BP2 ̄ / ̄ MEFs To study the role of 4E - BPs in the cell's response to virus infections ex vivo , MEFs ...
Page 324
... MEFs are resistant to infection by other viruses . Wild - type and 4E - BP1 ̄1- 4E - BP2 MEFs were infected with positive and negative strand RNA viruses , such as Sindbis virus ( alphavirus , positive strand ) , encephalomyocarditis ...
... MEFs are resistant to infection by other viruses . Wild - type and 4E - BP1 ̄1- 4E - BP2 MEFs were infected with positive and negative strand RNA viruses , such as Sindbis virus ( alphavirus , positive strand ) , encephalomyocarditis ...
Page 327
... MEFs . An increase in IRF - 7 expression iggers type - I IFN production , which subsequently evokes a tran- riptionally dependent positive feedback regulation of IRF - 7 signal- 1g33,34 . Consistent with this , we showed that the ...
... MEFs . An increase in IRF - 7 expression iggers type - I IFN production , which subsequently evokes a tran- riptionally dependent positive feedback regulation of IRF - 7 signal- 1g33,34 . Consistent with this , we showed that the ...
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activity adenovirus analysis antibody applications assay atoms binding Biol Biology cancer candidate carbon CD8 T cells Center complex correlation CP violation crystals cytosine desalination detected differentiation DNA methylation drug effect electron energy environment enzyme experiments function gene expression genetic genome human images increase infection Institute interactions isotopic ketyl Lett levels magnetic mantle measured mechanism MEFs membrane methylation mGluR2 mice microRNA molecular molecules mouse mRNA mutant Nature Nature Publishing Group Naturejobs neuronal observed online version paper at www.nature.com/nature pars tuberalis peptide peridotites phosphotyrosine photon Phys PKM2 plant plasmasphere population position predicted production protein pS2 promoter pyruvate kinase quantum receptor region regulation response ribosome role samples SATB1 says Science scientists sequence shown shRNA signal specific structure studies Supplementary Fig Supplementary Table target tion transcription tumour University vivo wild-type