Nature, Volume 452Sir Norman Lockyer Macmillan Journals Limited, 2008 - Electronic journals |
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Page 187
... SATB1 is a genome organizer that tethers multiple genomic loci and recruits chromatin - remodelling enzymes to regulate chromatin structure and gene expression . Here we show that SATB1 is expressed by aggressive breast cancer cells and ...
... SATB1 is a genome organizer that tethers multiple genomic loci and recruits chromatin - remodelling enzymes to regulate chromatin structure and gene expression . Here we show that SATB1 is expressed by aggressive breast cancer cells and ...
Page 189
... SATB1 pro- ein became hardly detectable by immunoblotting and its mRNA devels were substantially reduced by 70 % and 90 % in both SATB1- RNA1 and SATB1 - shRNA2 expressing cells , respectively ( Fig . 2a ) . ATB1 expression remained ...
... SATB1 pro- ein became hardly detectable by immunoblotting and its mRNA devels were substantially reduced by 70 % and 90 % in both SATB1- RNA1 and SATB1 - shRNA2 expressing cells , respectively ( Fig . 2a ) . ATB1 expression remained ...
Page 190
... SATB1 shRNA1 or SATB1 shRNA2 cells ( Fig . 3a ) . The presence of human cancer cells in each lung was verified by polymerase chain reaction with reverse transcription ( RT - PCR ) . Our data indicate that SATB1 is necessary for the ...
... SATB1 shRNA1 or SATB1 shRNA2 cells ( Fig . 3a ) . The presence of human cancer cells in each lung was verified by polymerase chain reaction with reverse transcription ( RT - PCR ) . Our data indicate that SATB1 is necessary for the ...
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activity adenovirus analysis antibody applications assay atoms binding Biol Biology cancer candidate carbon CD8 T cells Center complex correlation CP violation crystals cytosine desalination detected differentiation DNA methylation drug effect electron energy environment enzyme experiments function gene expression genetic genome human images increase infection Institute interactions isotopic ketyl Lett levels magnetic mantle measured mechanism MEFs membrane methylation mGluR2 mice microRNA molecular molecules mouse mRNA mutant Nature Nature Publishing Group Naturejobs neuronal observed online version paper at www.nature.com/nature pars tuberalis peptide peridotites phosphotyrosine photon Phys PKM2 plant plasmasphere population position predicted production protein pS2 promoter pyruvate kinase quantum receptor region regulation response ribosome role samples SATB1 says Science scientists sequence shown shRNA signal specific structure studies Supplementary Fig Supplementary Table target tion transcription tumour University vivo wild-type