Clinical Infectious Diseases: A Practical Approach

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Richard K. Root, Francis Waldvogel, Lawrence Corey, Walter E. Stamm
Oxford University Press, 1999 - Medical - 1013 pages
Until now, those in need of information on infectious diseases had to choose between encyclopedic reference texts or the infectious diseases sections in standard textbooks in internal medicine. Now there is a better alternative-Clinical Infectious Diseases fills the long-standing need for a practical yet comprehensive work that offers easy, convenient access to the topic. Of interest to internists, infectious disease specialists, and residents in training, the book is structured to give the reader essential information about the etiology and pathogenesis of various infectious diseases, and focuses on the clinical issues of managing, diagnosing, and treating patients with all types of infection. The editors and contributors are internationally known and recognized experts, and aim to validate the increasingly universal approaches to the diagnosis and treatment of infections worldwide. Emphasizing the clinical presentation of the patient by organ-system, diagnostic considerations including geographic, anatomic and microbiologic concerns, are addressed in detail. Diagnostic algorithms are provided, and specific choices of antimicrobial therapy are discussed and compiled in a user-friendly tabular format. Preventive measures for different types of infections are also addressed. Sections devoted to infections in special patient/risk groups, such as the post operative patient, the patient with immunodeficiency, the trauma patient, and the burn patient are included, as well as coverage of infections of travelers to tropical countries, and patients who have been bitten or scratched by animals or insects. A detailed presentation on HIV infection includes discussions of epidemiology, pathogenesis, immunology, clinical manifestations and antiviral treatment, as well as management of opportunistic infections.
 

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Contents

Historical Notes on Infectious Disease
1
Infectious Diseases An Overview
7
Pathophysiology of Infectious Diseases
17
Microbes and Virulence Factors Bacteria
19
Pathophysiology of Viruses and Viral Diseases
27
Parasitic Protozoa and Helminths
37
Fungi and Fungal Diseases
43
Epidemiology in Clinical Infectious Diseases
53
Cellulitis and Abscesses
501
Infectious Diseases with Lymphadenopathy
505
Upper Respiratory Tract Infections
513
Bronchitis and Bronchiectasis
523
Acute Pneumonia
529
Cavitary Pulmonary Disease
539
Diffuse Pulmonary Infiltrates and Acute Respiratory Distress Syndrome
557
Pleurisy and Empyema
565

Epidemiology and Control of Infectious Diseases in Health Care Facilities
61
Host Responses to Infection Fever Hyperthermia and Hypothermia
71
The Acute Inflammatory Response
83
The Specific Immune Response
91
Diagnostic Methods in Infectious Disease
109
Modern Imaging Techniques in Infectious Disease
111
Hematologic Alterations in Infectious Disease Patients
121
Metabolic and Endocrine Alterations in Infectious Disease Patients
133
Specimen Management and Rapid Detection of Infectious Agents
137
Clinical Bacteriology
145
Clinical Virology
159
Clinical Mycology
169
Clinical Parasitology
181
Rickettsia and Chlamydia
195
Antimicrobial Drugs Principles and Usage
207
Mechanisms of Antimicrobial Action and Resistance
209
Pharmacology of Antimicrobials
217
Antimicrobial Toxicities and Drug Interactions
225
Selection of Antimicrobials for Treatment
233
Outpatient Parenteral Therapy of Serious Infections
241
Control of Antimicrobial Usage
245
Penicillins
249
Cephalosporins
257
Other Betalactam Antibiotics Penems Carbapenems and Monobactams
265
Aminoglycosides
273
Glycopeptides
285
Macrolides and Clindamycin
291
Tetracyclines and Chloramphenicol
299
Fluoroquinolones
305
Sulfonamides and Trimethoprim
313
Miscellaneous Antibacterial Drugs
319
Antimycobacterial Drugs
327
Antimicrobial Therapy for Bacterial Diseases
337
Antiviral Drugs and Therapy
349
Antiparasitic Drugs and Therapy
365
Antifungal Drugs
389
Selection of Antifungal Drugs for Deep Mycoses
397
Vaccines and Immunomodulatory Agents
405
Principles of Vaccine Development and Immunoprophylaxis
407
Passive Immunoprophylaxis and Treatment
411
Specific Vaccines
415
Growth Factors Immunomodulators and Cytokines
427
Infectious Disease Syndromes
437
Approach to the Patient with Fever Acute Febrile Illness
439
Fever in Hospitalized Patients
449
Fever of Unknown Origin
459
Bacteremia Sepsis and Septic Shock
471
Infections with Rash
483
Intraoral Infections
573
Diarrhea and Gastroenteritis
581
Hepatitis
589
Pyogenic Biliary Tract and Hepatic Infections
597
Infectious Complications of Pancreatitis
605
Peritonitis and Intraabdominal Abscesses
613
Infective Endocarditis
621
Intravenous CatheterRelated Infections Suppurative Thrombophlebitis and Mycotic Aneurysms
637
Myocarditis and Pericarditis
643
Urinary Tract Infections
649
Genital Herpes Syphilis and Genital Ulcer Disease
657
Urethritis Epidydimitis Orchitis Prostatitis
669
Vulvovaginitis Cervicitis and Pelvic Inflammatory Disease
681
Meningitis
689
Encephalitis
703
Infections Associated with Myelopathy Radiculopathy and Neuropathy
715
Focal Central Nervous System Infections
723
Ocular and Periocular Infections
733
Osteomyelitis
741
Infectious and Postinfectious Arthritis
757
Myositis and Fasciitis
767
Chronic Fatigue Syndrome
773
Infections in Special PatientRisk Groups
781
Postsurgical Wound Infections
783
Burn Infections
789
Infections Complicating Traumatic Injury
795
Prosthetic Device Infections
801
Infection in the Immunodeficient Patient
809
Infection in the Organ Transplant Recipient
821
Hematopoietic Stem Cell Transplantation
829
Infection in the Malnourished Patient
839
Intravenous Drug Abuse and Infection
849
Alcohol Abuse Host Defenses and Infection
853
Fever in Travelers to Tropical Countries
859
Endemic and Travelers Diarrhea in Tropical Countries
875
Eosinophilia in Travelers to Tropical Countries
881
Infections after Animal Bites and Scratches
885
EctoparasiteRelated Diseases
891
Human Immunodeficiency Virus and AIDS
903
Epidemiology and Prevention
905
AIDS Pathogenesis Molecular Biology and Virology of HIV
915
AIDS Immunology
927
Clinical Manifestations of HIV Infection and AIDS
937
Antiretroviral Therapy
959
Therapy of Opportunistic Infections
965
Vaccines
977
Index
981
Copyright

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About the author (1999)


Richard Root, M.D., is Professor and Vice Chairman of the Department of Medicine, University of Washington School of Medicine, and Chief of the Medical Service, Harborview Medical Center, Seattle.
Francis Waldvogel, M.D., is Chairman of the Department of Medicine at the University of Geneva, Switzerland.

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